popari.model.Popari.estimate_parameters

popari.model.Popari.estimate_parameters#

Popari.estimate_parameters(update_spatial_affinities=True, differentiate_spatial_affinities=True, differentiate_metagenes=True, simplex_projection_mode='exact', edge_subsample_rate=None, synchronize=True)[source]#

Update parameters for each replicate.

Parameters:

  • update_spatial_affinities (bool) – If specified, spatial affinities will be updated during this iteration. Default: True

  • edge_subsample_rate (float | None) – Fraction of adjacency matrix edges that will be included in optimization of Sigma_x_inv.

  • differentiate_spatial_affinities (bool)

  • differentiate_metagenes (bool)

  • simplex_projection_mode (bool)

  • synchronize (bool)

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