popari.simulation_framework.MultiReplicateSyntheticDataset

class popari.simulation_framework.MultiReplicateSyntheticDataset(replicate_parameters, dataset_constructor, random_state=0, verbose=0)

Synthetic multireplicate dataset to model biological variation and batch effects in spatial transcriptomics data.

Methods

annotate_replicate_domain(replicate_name[, ...])
assign_domain_labels()
calculate_neighbors(**neighbors_kwargs)
simulate_expression()

Parameters:

• replicate_parameters (dict[SimulationParameters])

• dataset_constructor (SyntheticDataset)